David M replied: "It's not a drug-drug interaction that is the problem. It's more like a 'one drug or the other' problem. If 'someone' is on an SSRI like Paxil, taking ecstacy while on that SSRI will have little to no effect. Most probably, no effect at all. This is because all of the seratonin receptors that are normally available to 'feel the effect' are no longer available...i.e. they are occupied by the SSRI. That is why people have to stop taking SSRI's for days and even weeks before rolling. That being said. it is VERY INADVISABLE for someone to try to do one while on the other because all of the benefits gained by being on the SSRI medication will be lost when they stop taking it. Going on and off SSRI's is serious business and shouldn't be done carelessly or without regard."
I Richard KHC replied: "What david said is true, The main reason people stop taking it awhile before is because you will not feel as good as you normally would so it is a waste of the ecstasy.
Here is a better place to ask this question, or just search for it someone may have already asked it."
Drug interaction - Tryptophan in protein and Paxil? I have been taking Whey Protien that has 437 mg of Tryptophan per scoop and I take about 6 scoops per day. I also take a prescrption Paxil which is a SSRI is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Paroxetine affects chemicals in the brain that may become unbalanced.
Paroxetine is used to treat depression, obsessive-compulsive disorder, anxiety disorders, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD).
I have been feeling kind of dizzy and different the past 1-2 weeks and didn't know what it could be from then I read that you are not suppose to take SSRI with Tryptophan because it can cause Serotonin syndrome -Serotonin syndrome which is pretty much too much serotonin -
My only question is I only take 10mg of paxil a day and have been taking this protein for about 3 months. Do you think its this Serotonin Syndrome is kicking in now or would it already have happened? Anyone else take Paxil with a lot of protein and have this happen? Any advice would be appreciated. Thanks
Casey replied: "I have read pretty in-depth about serotonin syndrome / 'serotonin storm' before, and it's quite the serious thing.
However, I don't know much about the combination of the SSRI and Tryptophan, so I would suggest talking to your or a doctor (the one who perscribed you the later of the to drugs, perhaps), before quitting either drug, and also tell him about your serotonin syndrome idea. And you should do it rather quickly....
However, if you were not perscribed these drugs (easy to get or illegally obtained), then perhaps you could stop using them? Or one of them? Or something?
There is a website you can go to, called Bluelight. It's at Bluelight.ru, I'd suggest registering and posting your question in the basic drug discussion. It's in a Y!A style type of thing, but it's forums and completely about various drugs (perscription, non, etc). But be wary of some of the answers, as, just like here, anyone can post."

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