kellymc replied: "Please Read....I HAD an ectopic pregnancy. I found out at 7 weeks I was pregnant, didn't even know, as i got my period on time. I found out on January 9th. I had to go to the ER, The hospital gave me a shot of methotrexate on January 17th. They say methotrexate is 90% effective. My levels were going down perfeclty. They started at 6,500, then 3,500, then 750. But just 18 days after the shot, my fallopen tube ruptured, I had to go to the ER and have surgery. I don't want to say this to scare anyone, but I want you to be careful. I lost 5 pints of blood and almost lost my life. It was very horrible. If you are working, I suggest taking time off, until this is all over with, no unnecessary stress. I had bleeding for about 3-4 days after the shot and a tiny bit of spotting here and there. The first few days you will have period like cramps. If your fallopan tube ruptures, you will know it. I am going to tell you what signs to look out for. It will feel like this: If it ruptures, you will feel very very constipated, like x 10. Your stomach will get alot bigger and it will be hard for you to sit down, especially. It will feel like you ate the wrong thing! soon after 20-30 minutes at the most, you will feel very dizzy, or near faitness, or pass out. You have no more than a few hours to get help, otherwise it's fatal. Bleeding internally, you need surgery. I don't wanna scare anyone, it's just a concern. If you feel any of these signs, PLEASE don't hesitate! call 911 and go to the hospital and tell them what's wrong. This doesn't mean it's going to happen to you, but it's a concern. There is still a chance it can rupture. I wouldn't want anyone to go through what I did. It sucked! I lost my left fallpoan tube. so I can still have kids but I only have one tube, not two. Once it ruptures, it's very very difficult for a doctor to save that tube. If the shot works for you, It will be over, when your levels reached 0 twice in a row. So I really hope the shot works for you and I will keep you in my prayers. good luck with everything."

Jonna TTC#1 replied: "I'm sorry hun I have never heard of that. I know that methotrexate is used for arthritis, but never heard of that before. Sorry that you have to do this, and there is always next month to try again!"